p75NTR--live or let die.

Neurotrophins Live or Let Die: Does p75NTR Decide?

However, enhancing neurotrophin binding is not the Cornell University Medical College only role for p75. A number of reports suggest that it New York, New York 10021 also modulates trk signaling. While it is clear that trk †Growth Factor and Regeneration Group signaling can occur in the absence of p75, the reDepartment of Neuroscience sponses are increased in its presence. For example, Max Delb...

TrkA mediates developmental sympathetic neuron survival in vivo by silencing an ongoing p75NTR-mediated death signal

Developmental sympathetic neuron death is determined by functional interactions between the TrkA/NGF receptor and the p75 neurotrophin receptor (p75NTR). A key question is whether p75NTR promotes apoptosis by directly inhibiting or modulating TrkA activity, or by stimulating cell death independently of TrkA. Here we provide evidence for the latter model. Specifically, experiments presented here...

Live or let die; who decides an incompetent's fate? In re Storar and In re Eichner.

Live and Let Die: LSC-Based Verification of UML-Models

We present a strategy for automatic formal verification of Live Sequence Chart (LSC) specifications against UML models in the semantics of [7] employing the symmetry-based technique of Query Reduction [18, 34, 44] and the abstraction technique Data-type Reduction [34]. Altogether this allows for automatic formal verification without providing finite bounds on the numbers of objects created duri...

Let Live and Let Die: Handling the State of Hash-based Signatures

Real-world use of digital signatures currently relies on algo­ rithms that will be broken once quantum computers become available. Quantum-safe alternatives exist; in particular, hash-based schemes offer adequate performance and security and are seen as a fitting solution for post-quantum signatures. Unfortunately, they are not used at large because practical hurdles have not yet been overcome....